I did my Ph.D. in Paris (France) in Ciaràn Condon’s lab, where I studied RNA maturation and regulation of gene expression in the Gram-positive model organism Bacillus subtilis. In Jade’s lab, I’m interested in how the alarmone (p)ppGpp (a stress signaling molecule) affects the bacterial physiology, especially how (p)ppGpp tunes the translation machinery in response to stress. If I’m not in the lab, I might be hiking in Wisconsin’s State Parks, or baking something (likely containing chocolate ^^).
Publications
- Fung DK, Trinquier AE, Wang JD (2023) Crosstalk between (p)ppGpp and other nucleotide second messengers. Curr. Opin. Microbiol. 76:102398 PMC10842992 · Pubmed · DOI
- Deves V, Trinquier A, Gilet L, Alharake J, Leroy M, Condon C, Braun F (2023) Identification of a new substrate for the ribosome associated endoribonuclease Rae1 reveals a link to the B. subtilis response and sensitivity to chloramphenicol. bioRxiv. · DOI
- Trinquier A, Condon C, Braun F (2023) Effect of tRNA Maturase Depletion on Levels and Stabilities of Ribosome Assembly Cofactor and Other mRNAs in Bacillus subtilis. Microbiol Spectr. 11(2):e0513422 PMC10100781 · Pubmed · DOI
- Trinquier A, Durand S, Braun F, Condon C (2020) Regulation of RNA processing and degradation in bacteria. Biochim Biophys Acta Gene Regul Mech. 1863(5):194505 · Pubmed · DOI
- Pellegrini O, Gilet L, Trinquier A, Tolcan A, Allouche D, Durand S, Braun F, Condon C (2020) Assay of Bacillus subtilis Ribonuclease Activity In Vitro. In: Boudvillain M. (eds) RNA Remodeling Proteins. Methods Mol Biol. 2209:403-424 · Pubmed · DOI
- Gilet L, Pellegrini O, Trinquier A, Tolcan A, Allouche D, Braun F, Durand F, Condon, C (2020) Analysis of Bacillus subtilis Ribonuclease Activity In Vivo. In: Boudvillain M. (eds) RNA Remodeling Proteins. Methods Mol Biol. 2209:387-401 · Pubmed · DOI
- Oerum S, Dendooven T, Catala M, Gilet L, Dégut C, Trinquier A, Bourguet M, Barraud P, Cianferani S, Luisi BF, Condon C, Tisné C (2020) Structures of B. subtilis maturation RNases captured on 50S ribosome with Pre-rRNAs. Mol Cell. 80(2):227-236.e5 PMC7610893 · Pubmed · DOI
- Trinquier A (2019) Coupling between transfer RNA maturation and ribosomal RNA processing in Bacillus subtilis (Doctoral dissertation, Université Paris Cité).
- Trinquier A, Ulmer JE, Gilet L, Figaro S, Hammann P, Kuhn L, Braun F, Condon C (2019) tRNA maturation defects lead to inhibition of rRNA processing via synthesis of pppGpp. Mol Cell. 74(6):1227-1238.e3 · Pubmed · DOI
- Riley EP, Trinquier A, Reilly ML, Durchon M, Perera VR, Pogliano K, Lopez‐Garrido J (2018) Spatiotemporally regulated proteolysis to dissect the role of vegetative proteins during Bacillus subtilis sporulation: cell‐specific requirement of σH and σA. Mol Microbiol. 108(1):45-62 PMC6467272 · Pubmed · DOI