Education: BSc in Peking University; PhD in UW-Madison
Scientific interest: nucleotide alarmone, metabolome
Hobby: History reading, video game
Publications
- Lee YT, Savini M, Chen T, Yang J, Zhao Q, Ding L, Gao SM, Senturk M, Sowa J, Wang JD, Wang MC (2023) Mitochondrial GTP Metabolism Regulates Reproductive Aging. Dev. Cell. 58:1-14
- mBio. 13(6):e0242222 PMC9765508 Pubmed DOI
- Giammarinaro PI, Young MKM, Steinchen W, Mais C-N, Hochberg G, Yang J, Stevenson DM, Amador-Noguez D, Paulus A, Wang JD, Bange G (2022) Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nat. Microbiol. 7(9):1442-1452 · Pubmed · DOI
- Yang J, Barra JT, Fung DK, Wang JD (2022) Bacillus subtilis produces (p)ppGpp in response to bacteriostatic antibiotic chloramphenicol to prevent its potential bactericidal effect. mLife 1(2):101-113 · DOI
- Anderson BW, Schumacher MA, Yang J, Turdiev A, Turdiev H, Schroeder JW, He Q, Lee VT, Brennan RG, Wang JD (2022) The nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus. Nucleic Acids Res. 50(2):847-866 PMC8789054 · Pubmed · DOI
- Updegrove TB, Harke J, Anantharaman V, Yang J, Gopalan N, Wu D, Piszczek G, Stevenson DM, Amador-Noguez D, Wang JD, Aravind L, Ramamurthi KS (2021) Reformulation of an extant ATPase active site to mimic ancestral GTPase activity reveals a nucleotide base requirement for function. eLife 10:e65845 PMC7952092 · Pubmed · DOI
- Yang J, Anderson BW, Turdiev A, Turdiev H, Stevenson DM, Amador-Noguez D, Lee VT, Wang JD (2020) The nucleotide pGpp acts as a third alarmone in Bacillus, with functions distinct from those of (p) ppGpp. Nat. Commun. 11(1):5388 PMC7584652 · Pubmed · DOI
- Fung DK, Yang J, Stevenson DM, Amador-Noguez D, Wang JD (2020) Small Alarmone Synthetase SasA Expression Leads to Concomitant Accumulation of pGpp, ppApp, and AppppA in Bacillus subtilis. Front. Microbiol. 11:2083 PMC7492591 · Pubmed · DOI
- Chen M, Zhao Z, Yang J, Peng K, Baker MAB, Bai F, Lo C-J (2017) Length-dependent flagellar growth of Vibrio alginolyticus revealed by real time fluorescent imaging. eLife. 6:e22140 PMC5300704 · Pubmed · DOI
- Buda R, Liu Y, Yang J, Hegde S, Stevenson K, Bai F, Pilizota T (2016) Dynamics of Escherichia coli‘s passive response to a sudden decrease in external osmolarity. Proc Natl Acad Sci U S A. 113(40):E5838-E5846 PMC5056102 · Pubmed · DOI